CPHA Canvax

"Although the literature is well-established on protection and waning of immunity following infection with previous SARS-CoV-2 strains and COVID-19 vaccination, little is known about protective immunity following Omicron infection. Assessment of this must also consider key Omicron sublineages (BA.1, BA.2, BA.4 and BA.5), as each sublineage has a unique complement of mutations. A review of existing evidence was conducted to answer a series of questions. When there is a history of Omicron infection with one strain what is the risk of reinfection with the same Omicron strain or reinfection with a different Omicron strain? How does the risk of reinfection vary by the history of vaccination and/or infection prior to the first Omicron infection? What are the trends in in vitro immunogenicity studies, measuring neutralizing antibodies and T and B cell activity, after an Omicron infection?" - Omicron infection: Is there protective immunity after infection? 

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Monitoring and Surveillance,Outbreaks and Pandemics,COVID-19 Monitoring and Surveillance
Outbreaks and Pandemics
COVID-19

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